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Cyclophosphamide (Cytoxan) belongs to a class of drugs known as alkylating agents, which have been used to treat some types of cancer. It is also considered a potent immunosuppressant�a medicine that can decrease the immune response. Cyclophosphamide blocks the production of the deoxyribonucleic acid (DNA) in cells.
DISCONTINUED BRAND: Cytoxan in the US. USES: Cyclophosphamide is used alone for the treatment of several types of cancers, but often in combination with other drugs to treat breast cancer, leukemia and ovarian cancer. It also is approved for treating nephrotic syndrome (a disease of the kidneys) in children.Ju
The “gold standard” drug regimen for treating severe lupus is Cytoxan in combination with the corticosteroid methylprednisolone. Cytoxan is actually a cancer drug, but in lupus patients, it’s used to treat serious kidney inflammation (including lupus nephritis) or other complications that threaten the organs.
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Common side effects of Cytoxan include: nausea or vomiting (may be severe), loss of appetite, stomach pain or upset, diarrhea, temporary hair loss, a wound that will not heal, missed menstrual periods, changes in skin color (darkening), or.
In addition to cancer, cyclophosphamide may cause a variable amount of bleeding from the bladder, a complication known as �hemorrhagic cystitis�. … If any bleeding from the bladder is discovered while a patient is taking cyclophosphamide, the medicine should be stopped until the bladder can be evaluated by cystoscopy.
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